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  Bicar® CODEX

Product description

Chemical names: Sodium hydrogen carbonate, Sodium bicarbonate, Natrii hydrogenocarbonas, Carbonic acid mono sodium salt, Baking soda.
Sodium Hydrogencarbonate is widely used in pharmaceutical formulations, for pH adjustment, as buffering agent, as antacid or in dialysis solutions. In effervescent tablets in conjunction with citric or tartaric acid it releases carbon dioxid, which enhances the dispersion and dissolution of medication.

Depending on those different applications in ethical medicines or OTC products Sodium Hydrogencarbonate can be used as an active pharmaceutical ingredient (API), as an excipient or as a component in a medical device.

BICAR® CODEX is the right product when you use a pharmaceutical Sodium Hydrogen as excipient, in Hemodialysis, or as high purity material for chemical reactions.

BICAR® Codex fulfills the requirements of the European Pharmacopoeia 5th edition and of the American Pharmacopoeia USP 30.

The following restriction has to be taken into account: BICAR® CODEX is not intended to be used in parenteral formulations or in peritoneal dialysis. Those applications stipulate more severe and specific requirements, which are not fulfilled by BICAR® CODEX.

Chemical and physical properties

BICAR® CODEX consists of white crystals or of white, granular or crystalline powder. It is soluble in water and decomposes during heating in the dry state or in solution to sodium carbonate under evolution of CO2 gas.

2 NaHCO3 --> CO2 + H2O + Na2CO3

CO2 gas is also formed during reaction with acids:

NaHCO3 + HCl --> NaCl + CO2 + H2O

NaHCO3 + CH3CHOHCOOH --> CH3CHOHCOONa + CO2 + H2O

 

The pH value of Sodium Hydrogen Carbonate in an aqueous 1 % solution is about 8,4.

BICAR® CODEX is available in different particle size distributions.

 

For more technical documentation, please contact us.

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Date of last update: 6/5/2010